PIC09 Multi-Mode Plate Reader

Multi-Mode Plate Reader
Core Functions & Features
- Multi-mode detection: absorbance, fluorescence intensity (including FRET), time-resolved fluorescence (TRF, TR-FRET), fluorescence polarization, luminescence (including BRET), AlphaScreen/AlphaLISA, and nephelometry
- Patented LVF monochromator technology: flexible wavelength and bandwidth adjustment, combining high sensitivity with filter-like stability
- Enhanced Dynamic Range (EDR): covers up to 8 orders of magnitude in a single measurement without manual gain adjustment
- Automated Z-height focus: adjusts focus for each well to improve signal consistency
- Spectrometer mode: completes full-spectrum scanning (220–1000 nm, 1 nm resolution) in 1 second
- Real-time kinetic monitoring: up to 100 reads per second, supporting live-cell analysis
- Integrated incubation and gas control: compatible with CO₂/O₂ regulation, temperature control, and shaking systems, ideal for long-term cell-based experiments
Applicable Fields
- Drug discovery and high-throughput screening (HTS): multicolor labeling, FRET/BRET, Alpha-based drug assays
- Molecular and cell biology research: gene expression, protein interactions, and signaling pathway analysis
- Live-cell dynamic monitoring: cell metabolism, cytotoxicity assays, and long-term real-time imaging
- Clinical research and diagnostic development: immunoassays (ELISA), molecular assay validation platforms
- Protein and enzyme kinetics: reaction rate analysis and inhibitor efficacy testing
Performance & Achievements
- Successfully applied in Protein A binding analysis, verifying protein purification and recovery efficiency